Chronic Lymphocytic Leukemia Newsfeed

Research from E.J. Lewintre and co-authors reveals new findings on chronic lymphocytic leukemia.

Chronic lymphocytic leukemia is an adult-onset leukemia with a heterogeneous clinical behavior. When chronic lymphocytic leukemia cases were divided on the basis of IgV mutational status, widely differing clinical courses were revealed, researchers in Valencia, Spain report (see also Chronic ...

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New findings reported from Duke University describe advances in chronic lymphocytic leukemia.

Survival of chronic lymphocytic leukemia cells requires sustained activation of the antiapoptotic PI-3-K/Akt pathway, and many therapies for CLL cause leukemia cell death by triggering apoptosis. Blood lipoprotein particles are either pro- or antiapoptotic, researchers in the United States ...

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Findings from St. Bartholomew's Hospital broaden understanding of chronic lymphocytic leukemia.

Chronic lymphocytic leukemia remains incurable with standard therapy. Most patients with CLL have an indolent clinical course, but it is possible to identify patients with high-risk disease, investigators in London, the United Kingdom report . Younger ...

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Data on chronic lymphocytic leukemia immunology described by S. Molica et al.

New investigation results, 'Increased serum BAFF (B-cell activating factor of the TNF family) level is a peculiar feature associated with familial chronic lymphocytic leukemia,' are detailed in a study published in Leukemia Research. In a series of 84 chronic lymphocytic leukemia patients we ...

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Research from Uppsala University, Department of Medical Sciences yields new data on chronic lymphocytic leukemia therapy.

Data detailed in 'Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination' have been presented. According to a study from Uppsala, Sweden, The mammalian target of rapamycin inhibitor rapamycin and its analogues show ...

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Researchers at Medical University of Vienna target chronic lymphocytic leukemia.

According to recent research from Vienna, Austria, Few data are available concerning the prevalence of autoimmune disease or chronic infections in chronic lymphocytic leukemia patients at diagnosis as well as their clinical outcome. We studied the frequency of such chronic conditions in relation to ...

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Report summarizes chronic lymphocytic leukemia immunology study findings from Nanjing Medical University, Department of Hematology.

Research findings, 'Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia,' are discussed in a new report. The incidence of chronic lymphocytic leukemia in Asian countries is lower than that in the Western ones, where CLL is the most ...

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Targeted approaches may lead to better treatment of chronic lymphocytic leukemia.

2003 SEP 4 - - Targeted approaches may lead to better treatment of chronic lymphocytic leukemia. Chronic lymphocytic leukemia therapy has changed dramatically over the past decade, with recent studies supporting the use of fludarabine as the initial therapy for ...

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New chronic lymphocytic leukemia prognosis research from General Hospital outlined.

A new study, 'Controversies in the front-line management of chronic lymphocytic leukemia,' is now available. Once considered a simple homogeneous disease, chronic lymphocytic leukemia is now recognized to be a heterogeneous lymphoid malignancy with patients classified into low, intermediate, ...

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Data on chronic lymphocytic leukemia immunotherapy reported by researchers at University of London, Institute of Cancer.

Scientists discuss in 'Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug' new findings in chronic lymphocytic leukemia. Cancer is associated with immune deficiency, but the biologic basis of this is poorly defined. ...

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FDA Appeal Decision Indicates That Genasense Approval In Chronic Lymphocytic Leukemia Will Require Additional ...

Mon, 9 Mar 2009 12:17:10 +0100

Genta Incorporated (NASDAQ: GNTA) announced that the Food and Drug Administration's (FDA) Center for Drug Evaluation and Research (CDER) has decided that available data are not adequate to support approval of Genasense� (oblimersen sodium) Injection for treatment of patients with relapsed or refractory chronic lymphocytic leukemia (CLL).

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FDA Appeal Decision Indicates that Genasense� Approval in Chronic Lymphocytic Leukemia Will Require Additional ...

Fri, 6 Mar 2009 22:39:26 +0100

Genta Incorporated (NASDAQ: GNTA) announced that the Food and Drug Administrations (FDA) Center for ...

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Studies from University of Barcelona in the area of chronic lymphocytic leukemia published.

According to a study from Barcelona, Spain, The nucleoside analogue fludarabine is used in the treatment of chronic lymphocytic leukemia. It triggers p53-mediated apoptosis, although the mutational status of p53 does not fully account for heterogeneity in responsiveness to treatment. The aim of ...

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Cancer Acute Lymphoblastic Leukemia or Leukemia or Chronic Lymphocytic Leukemia or Chronic Myelogenous Leukemia or Acute Myelogenous Leukemia or Hairy Cell Leukemia.

M2 PRESSWIRE-15 March 2009-www.companiesandmarkets.com: Cancer Acute Lymphoblastic Leukemia or Leukemia or Chronic Lymphocytic Leukemia or Chronic Myelogenous Leukemia or Acute Myelogenous Leukemia or Hairy Cell Leukemia1994-2009 M2 COMMUNICATIONS LTD RDATE:15032009 -www.companiesandmarkets.com ...

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Studies from International Agency for Research on Cancer in the area of chronic lymphocytic leukemia epidemiology described.

Fresh data on chronic lymphocytic leukemia are presented in the report 'Ionizing radiation and risk of chronic lymphocytic leukemia in the 15-country study of nuclear industry workers.' According to recent research from Lyon, France, In contrast to other types of leukemia, chronic lymphocytic ...

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